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After surgery I was pronounced cancer free but still put in Aromasin. I found the side effects difficult especially insomnia. My schedule is busy and this plus muscle/joint pain is hard. I went off for several months during a vacation and felt far better. I returned to taking it and almost immediately the side effects returned. I have very mixed feelings about continuing. My health insurance covers it so thankfully expense is not an issue. I will probably continue as statistically the drug has proved valuable.

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Lonning PE, Bajetta E, Murray R, Tubiana-Hulin M, Eisenberg PD, Mickiewicz E, Celio L, Pitt P, Mita M, Aaronson NK, Fowst C, Arkhipov A, di Salle E, Polli A, Massimini G 2000 Activity of exemestane in metastatic breast cancer after failure of non steroidal aromatase inhibitors: a phase II trial.

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Other aromatase inhibitors, such as the first-generation aminoglutethimide, have limited use due to toxicity and lack of selectivity for the aromatase enzyme, necessitating concomitant corticosteroid supplementation in some cases.

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